It‘s best to avoid handling coins if you can. Scratched, dirty, or coins marred from handling have less value than those in mint condition. When it's absolutely necessary you should hold them on the edges.

It is usually not a good idea to clean coins, so if it has to be done, the process should be entrusted to an expert. A coin's patina, gradually developed over a period of time, might increase the coin's desirability, whereas cleaning the coin could make it less valuable.

Just about any holder that you find on the market will be enough to safely store your seated liberty quarters; just make sure your most valuable ones are safe from fingerprints, dust, and even moisture. Although the usual stapled or taped packets don’t provide optimum protection, there are other containers out there that also block moisture. A dry, temperature controlled area is the best storage area for collectible coins; storing in a basement or other damp location is never a good idea.